hrp0097fc6.6 | Pituitary, neuroendocrinology and puberty 1 | ESPE2023

Serum Kisspeptin and DLK1 levels as a tool for diagnosis and monitoring of central precocious puberty treatment in Thai girls

Onsoi Witchuwan , Numsriskulrat Nattakarn , Srilanchakon Khomsak , Aroonparkmongkol Suphab , Supornsilchai Vichit

Background: Kisspeptin and Delta-like 1 homolog (DLK1) are neuropeptides that regulate pubertal timing by activating and inhibiting the hypothalamic-pituitary-gonadal axis; consequently, measuring these biomarkers could potentially distinguish central precocious puberty (CPP) from premature thelarche (PT) girls and monitor CPP treatment.Objectives: To compare baseline serum kisspeptin and DLK1 levels in girls with CPP at...